Midway via his vocation, Cees Dekker reinvented himself. Just after several years of hardcore physics, he shifted his target to ‘nanobiology’ at the switch from the millennium. A expression he coined himself, as being a matter of truth.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
As a human being, I provide the biblical assignment to discover and use all the things in creation for the good thing about my neighbour. I tend not to experience any conflict among religion and science. Quite the opposite, my religion stimulates me to complete science, for being open up-minded in the world.’
I'm able to hardly imagine how I, as a geneticist, would have the ability to understand basic physics, let alone contend at the best. How did you go about this?
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart design and style in 2005. (nl)
Illustration (3) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is demonstrated in grey, the rim of your pore is highlighted in purple, along with a 3D rendering of the movement from the DNA rod is exhibited.
We condition microorganisms into kinds that deviate from their organic phenotype. Particularly, I will clearly show our capacity to form Reside E. coli bacteria into novel styles for instance rectangles, squares, triangles and circles.
2000, discovery that nanotubes can carry amazing large recent densities; fixed the controversial concern of Digital transportation via DNA molecules by measurements of insulating habits at The one molecule level; and demonstration of an AFM strategy for one-molecule manipulation of nanotubes
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Resolving the step size in condensin-pushed DNA loop extrusion identifies ATP binding given that the move-making course of action
An built-in microfluidic System for quantifying drug permeation throughout biomimetic vesicle membranes
‘That issues the artificial mobile, as A part of the Dutch ceesdekker.net BaSyC initiative. Craig Venter seemed top-down in Individuals times and identified about five hundred genes that happen to be minimally required for the performing cell. We want to glance base-up: how do we transfer from a several molecules to a complete biological technique?
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes
Lastly, I will briefly sketch a few of our Tips to check out the making of artificial cells, specially our to start with ways to determine artificial mobile division.